发明授权
- 专利标题： Sulfamato hydroxamic acid metalloprotease inhibitor
- 专利标题（中）： 磺酰胺异羟肟酸金属蛋白酶抑制剂
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申请号： US10084713申请日： 2002-02-26
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公开(公告)号： US06492367B1公开(公告)日： 2002-12-10
- 发明人: Gary A DeCrescenzo , Joseph G Rico , Terri Boehm , Jeffery N Carroll , Darren J Kassab , Deborah A Mischke , Shashidhar Rao
- 申请人： Gary A DeCrescenzo , Joseph G Rico , Terri Boehm , Jeffery N Carroll , Darren J Kassab , Deborah A Mischke , Shashidhar Rao
- 主分类号： A61K31496
- IPC分类号： A61K31496
摘要：
A sulfamato hydroxamic acid compound that inter alia inhibits matrix metalloprotease activity is disclosed as are a process for preparing the same, intermediate compounds useful in those syntheses, and a treatment process that comprises administering a contemplated sulfamato hydroxamic acid compound in a MMP enzyme-inhibiting effective amount to a host having a condition associated with pathological matrix metalloprotease activity.
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