发明授权
US06503901B1 Amino lactam sulfonamides as inhibitors of A&bgr; protein production
有权
氨基内酰胺磺酰胺作为Abeta蛋白质生产的抑制剂
- 专利标题： Amino lactam sulfonamides as inhibitors of A&bgr; protein production
- 专利标题（中）： 氨基内酰胺磺酰胺作为Abeta蛋白质生产的抑制剂
-
申请号： US09684718申请日： 2000-10-07
-
公开(公告)号： US06503901B1公开(公告)日： 2003-01-07
- 发明人: Lorin Andrew Thompson , Amy Qi Han
- 申请人： Lorin Andrew Thompson , Amy Qi Han
- 主分类号： C07D41312
- IPC分类号： C07D41312
摘要：
This invention relates to novel lactams having the Formula (I): to their pharmaceutical compositions and to their methods of use. These novel compounds inhibit the processing of amyloid precursor protein and, more specifically, inhibit the production of A&bgr;-peptide, thereby acting to prevent the formation of neurological deposits of amyloid protein. More particularly, the present invention relates to the treatment of neurological disorders related to &bgr;-amyloid production such as Alzheimer's disease and Down's Syndrome.
信息查询
