发明授权
US06506797B1 Substituted phenylpropionic acid derivatives as agonists to human peroxisome proliferator-activated receptor (PPAR) &agr;
失效
取代的苯丙酸衍生物作为人类过氧化物酶体增殖物激活受体（PPAR）α的激动剂
- 专利标题： Substituted phenylpropionic acid derivatives as agonists to human peroxisome proliferator-activated receptor (PPAR) &agr;
- 专利标题（中）： 取代的苯丙酸衍生物作为人类过氧化物酶体增殖物激活受体（PPAR）α的激动剂
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申请号： US10009175申请日： 2001-12-10
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公开(公告)号： US06506797B1公开(公告)日： 2003-01-14
- 发明人: Masahiro Nomura , Yukie Takahashi , Takahiro Tanase , Hiroyuki Miyachi , Masaki Tsunoda , Tomohiro Ide , Koji Murakami
- 申请人： Masahiro Nomura , Yukie Takahashi , Takahiro Tanase , Hiroyuki Miyachi , Masaki Tsunoda , Tomohiro Ide , Koji Murakami
- 优先权： JP11-162235 19990609; JP2000-157600 20000529
- 主分类号： A01N3712
- IPC分类号： A01N3712
摘要：
The invention provides novel substituted phenylpropanoic acid derivatives that activate by binding to receptor as ligands of human peroxisome preliferant-activated receptor &agr; (PPAR&agr;), and exhibit potent decreasing action on lipids in blood (cholesterol and triglyceride). It relates to a substituted phenylpropanoic acid derivatives represented by a general formula (1), their pharmaceutically acceptable salts and their hydrates, and processes for preparing them.
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