发明授权
- 专利标题: Spiropiperidine derivatives
- 专利标题(中): 螺哌啶衍生物
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申请号: US09616092申请日: 2000-07-13
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公开(公告)号: US06511975B1公开(公告)日: 2003-01-28
- 发明人: Takahide Nishi , Takeshi Yamaguchi , Yukiko Iio , Toshiyasu Takemoto , Katsuyoshi Nakajima
- 申请人: Takahide Nishi , Takeshi Yamaguchi , Yukiko Iio , Toshiyasu Takemoto , Katsuyoshi Nakajima
- 优先权: JP10-11112 19980123; JP10-132959 19980515
- 主分类号: C07D41306
- IPC分类号: C07D41306
摘要:
A compound of the formula (I) wherein R1 and R2 is a substituted or unsubstituted aryl group, or a substituted or unsubstituted heteroaryl group. A is CH2, CO or SO2. B is a single bond, alkylene or alkenylene. D is O or S. E is alkylene or alkenylene. wherein G is a substituted or unsubstituted cycloalkene ring, or a substituted cycloalkane ring. Ar is a substituted or unsubstituted aryl ring, or a substituted or unsubstituted heteroaryl ring. R3 is alkyl. n is 1-3. The invention includes a pharmacologically acceptable salt, ester or other derivative of a compound of the formula (I). The invention also provides pharmaceutical compositions and methods of treating specified diseases utilizing a compound of formula (I).
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