发明授权
US06525052B2 Compounds useful as reversible inhibitors of cysteine proteases
有权
可用作半胱氨酸蛋白酶的可逆抑制剂的化合物
- 专利标题： Compounds useful as reversible inhibitors of cysteine proteases
- 专利标题（中）： 可用作半胱氨酸蛋白酶的可逆抑制剂的化合物
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申请号： US09808439申请日： 2001-03-14
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公开(公告)号： US06525052B2公开(公告)日： 2003-02-25
- 发明人: Younes Bekkali , Eugene R. Hickey , Weimin Liu , Usha R. Patel , Denice M. Spero , Sanxing Sun , David S. Thomson , Yancey D. Ward , Erick R. R. Young
- 申请人： Younes Bekkali , Eugene R. Hickey , Weimin Liu , Usha R. Patel , Denice M. Spero , Sanxing Sun , David S. Thomson , Yancey D. Ward , Erick R. R. Young
- 主分类号： A61K31335
- IPC分类号： A61K31335
摘要：
Disclosed are novel cathepsin S, K, F, L and B reversible inhibitory compounds of the formula (Ia) and (Ib) where R2, R3, R4, R5, R6, R7, R8, Het and X are defined herein. The compounds are useful for treating autoimmune and other diseases. Also disclosed are processes for making such novel compounds.
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