发明授权
US06531511B1 2-adamantanemethanamine compounds for treating abnormalities in glutamatergic transmission
失效
2-金刚烷甲胺化合物用于治疗谷氨酸能传递异常
- 专利标题： 2-adamantanemethanamine compounds for treating abnormalities in glutamatergic transmission
- 专利标题（中）： 2-金刚烷甲胺化合物用于治疗谷氨酸能传递异常
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申请号： US09890061申请日： 2001-10-16
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公开(公告)号： US06531511B1公开(公告)日： 2003-03-11
- 发明人: Roger John Gillespie , Nathaniel Julius Thomas Monck , Andrew James Bird , Simon Edward Ward
- 申请人： Roger John Gillespie , Nathaniel Julius Thomas Monck , Andrew James Bird , Simon Edward Ward
- 优先权： GB9901691 19990126
- 主分类号： A61K3113
- IPC分类号： A61K3113
摘要：
The use of a compound of formula (1), as disclosed in the specification, wherein R1, R2, R3, R4, R5 and R6 are independently selected from hydrogen, alkyl and aryl, or pharmaceutically acceptable salts thereof, with the proviso that wherein R1 to R4 and R6 are hydrogen, R5 is not selected from CH2CH2NHSO2CH3, CH2CH2NHSO2CF3 and methyl substituted by SO2NH2, SO3H, PO3H2, CONHOH or a heterocyclic group selected from formulae (a), (b), (c), (d) and (e) in the manufacture of a medicament for use in the treatment of a condition generally associated with abnormalities in glutamatergic transmission.
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