发明授权
US06544952B1 Synthesis of glycoconjugates of the globo-H epitope and uses thereof
失效
Globo-H表位的糖缀合物的合成及其用途
- 专利标题: Synthesis of glycoconjugates of the globo-H epitope and uses thereof
- 专利标题(中): Globo-H表位的糖缀合物的合成及其用途
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申请号: US09017611申请日: 1998-02-02
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公开(公告)号: US06544952B1公开(公告)日: 2003-04-08
- 发明人: Samuel J. Danishefsky , Philip O. Livingston , Govindaswami Ragupathi , In Jong Kim , Howard Scher , Susan Slovin
- 申请人: Samuel J. Danishefsky , Philip O. Livingston , Govindaswami Ragupathi , In Jong Kim , Howard Scher , Susan Slovin
- 主分类号: A01N11304
- IPC分类号: A01N11304
摘要:
The present invention provides a method of synthesizing a compound having the structure: as well as other related glycoconjugates useful as vaccines for inducing antibodies to epithelial cancer cells in an adjuvant therapy therefore, and in a method for preventing recurrence of epithelial cancer. The present invention also provides a vaccine comprising an amount of the compound described above effective to prevent the recurrence of cancer in a subject.
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