发明授权
US06548677B1 Method of producing 2-alkyl-3-(4,5-dihydroisoxazole-3-yl)-halobenzenes 有权
2-烷基-3-(4,5-二氢异恶唑-3-基) - 卤代苯的制备方法

Method of producing 2-alkyl-3-(4,5-dihydroisoxazole-3-yl)-halobenzenes
摘要:
A novel process for preparing the compounds of the formula I where: n is 0, 1 or 2; R1, R2 are C1-C6-alkyl; R3, R4, R5 are hydrogen or C1-C6-alkyl, or R4 and R5 together form a bond; R6 is Cl, Br, which comprises a synthesis sequence starting from 1,2-dialkylbenzenes of the formula II with subsequent halogenation to give 3,6-dihalo-1,2-dialkylbenzenes, haloalkylation to give benzyl bromides, oxidation to give benzaldehydes, oximation, reaction with alkenes to give isoxazoles, conversion into thioethers and, if appropriate, oxidation to give sulfenyl or sulfonyl derivatives of the formula I.
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