发明授权
US06562563B1 Compositions and mehtods for determining interactions of mitochondrial components, and for identifying agents that alter such interactions
失效
用于确定线粒体组分相互作用的组合物和方法，以及用于鉴定改变这种相互作用的试剂
- 专利标题： Compositions and mehtods for determining interactions of mitochondrial components, and for identifying agents that alter such interactions
- 专利标题（中）： 用于确定线粒体组分相互作用的组合物和方法，以及用于鉴定改变这种相互作用的试剂
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申请号： US09434354申请日： 1999-11-03
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公开(公告)号： US06562563B1公开(公告)日： 2003-05-13
- 发明人: Anne N. Murphy , William Clevenger , Sandra Eileen Wiley , Alexander Y. Andreyev , Luciano G. Frigeri , Gonul Velecelebi , Robert E. Davis
- 申请人： Anne N. Murphy , William Clevenger , Sandra Eileen Wiley , Alexander Y. Andreyev , Luciano G. Frigeri , Gonul Velecelebi , Robert E. Davis
- 主分类号： C12N500
- IPC分类号： C12N500
摘要：
Compositions and methods are provided for identifying agents that alter mitochondrial membrane permeability transition. The screening methods generally detect agents that alter the interaction between the mitochondrial adenine nucleotide translocator and cyclophilin D. Such agents may be used, for example, in the treatment of a variety of conditions associated with altered mitochondrial function.