发明授权
US06569858B2 12,13-(pyranosyl)-indolo[2,3-a]pyrrolo[3,4-c]carbazole and 12,13-(pyranosyl)-furo[3,4-c]indolo[2,3-a]carbazoles
失效
12,13-（吡喃糖基） - 吲哚并[2,3-a]吡咯并[3,4-c]咔唑和12,13-（吡喃糖基） - 呋喃并[3,4-c]吲哚并[2,3-a] 咔唑
![12,13-(pyranosyl)-indolo[2,3-a]pyrrolo[3,4-c]carbazole and 12,13-(pyranosyl)-furo[3,4-c]indolo[2,3-a]carbazoles](/docs/US/2003-05-27/US06569858B2/abs.jpg.600x600.jpg)
- 专利标题： 12,13-(pyranosyl)-indolo[2,3-a]pyrrolo[3,4-c]carbazole and 12,13-(pyranosyl)-furo[3,4-c]indolo[2,3-a]carbazoles
- 专利标题（中）： 12,13-（吡喃糖基） - 吲哚并[2,3-a]吡咯并[3,4-c]咔唑和12,13-（吡喃糖基） - 呋喃并[3,4-c]吲哚并[2,3-a] 咔唑
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申请号： US10010379申请日： 2001-11-05
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公开(公告)号： US06569858B2公开(公告)日： 2003-05-27
- 发明人: Michelle Prudhomme , Pascale Moreau , Fabrice Anizon , Christelle Marminon , Ghanem Atassi , Alain Pierre , Bruno Pfeiffer , Pierre Renard
- 申请人： Michelle Prudhomme , Pascale Moreau , Fabrice Anizon , Christelle Marminon , Ghanem Atassi , Alain Pierre , Bruno Pfeiffer , Pierre Renard
- 优先权： FR9914433 19991117
- 主分类号： C07D49044
- IPC分类号： C07D49044
![12,13-(pyranosyl)-indolo[2,3-a]pyrrolo[3,4-c]carbazole and 12,13-(pyranosyl)-furo[3,4-c]indolo[2,3-a]carbazoles](/abs-image/US/2003/05/27/US06569858B2/abs.jpg.150x150.jpg)
摘要：
A compound selected from those of formula (I): wherein: R1 and R2, which may be identical or different, represent a group of formula U-V wherein U represents single bond, or alkylene which is optionally substituted and/or unsaturated, and V is as defined in the description, G represents oxygen, or NR3 wherein R3 is as defined in the description, X represents hydrogen, hydroxy, alkoxy, mercapto or alkylthio, Y represents hydrogen, or X+Y represents carbonyl, X1 represents hydrogen, hydroxy, alkoxy, mercapto or alkylthio, Y1 represents hydrogen, or X1+Y1 represents carbonyl, R4, R5, and R6 are as defined in the description, its isomers, and pharmaceutically-acceptable acid or base addition salts thereof, and medicinal products containing the same are useful in the treatment of cancer.