A device (1) for the treatment of a region of a body comprises the following components, i.e.: a housing (2) which can be held in one hand, a tool (10) provided for treating the region of the body, drive means (14) for driving the tool (10), and compression force definition means (65) for defining a desired compression force obtaining between the tool (10) and the region of a body under treatment, as well as adjustment means (66) accommodated in the housing (2) for adjusting the range for a desired compression force.