发明授权
- 专利标题： Acyclic nucleoside derivatives
- 专利标题（中）： 无环核苷衍生物
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申请号： US09550554申请日： 2000-04-17
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公开(公告)号： US06576763B1公开(公告)日： 2003-06-10
- 发明人: Per Engelhardt , Marita Hogberg , Nils-Gunnar Johansson , Xiao-Xiong Zhou , Bjorn Lindborg , M. Robert Leanna , Michael Rasmussen
- 申请人： Per Engelhardt , Marita Hogberg , Nils-Gunnar Johansson , Xiao-Xiong Zhou , Bjorn Lindborg , M. Robert Leanna , Michael Rasmussen
- 优先权： SE9600613 19960216; SE9600614 19960216
- 主分类号： C07D47300
- IPC分类号： C07D47300
摘要：
Compounds of the Formula I where one of R1 and R2 is —C(O)CH(CH(CH3)2)NH2 or —C(O)CH(CH(CH3)CH2CH3)NH2; the other of R1 and R2 is —C(═O)C3-C21 saturated or monounsaturated, optionally substituted alkyl; and R3 is OH or H; and pharmaceutically acceptable salts thereof have utility as enhanced bioavailability antivirals against herpes and retroviral infections.
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