Invention Grant
US06597176B2 Method and apparatus for making measurements of patterns of magnetic particles in lateral flow membranes and microfluidic systems 有权
用于测量侧流膜和微流体系统中磁性颗粒图案的方法和装置

Method and apparatus for making measurements of patterns of magnetic particles in lateral flow membranes and microfluidic systems
Abstract:
An apparatus is provided for quantitatively determining amounts and identities of substances whithin patterns of magnetic particles, such as within lateral flow membranes, microfludic systems, and the like. Magnetic particles are complexed with substances to be determined and are excited in an oscillating magnetic field. The magnetizations of the magnetic particles are thereby caused to oscillate at the excitation frequency to create their own fields. These fields are inductively coupled to at least one sensor such as sensing coils fabricated in a gradiometer configuration. The output signals from the sensing coils are appropriately amplified and processed to provide useful output indications.
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