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发明授权
US06610301B1 Immunologically active proteins from Borrelia burgdorferi, nucleic acids which encode them, and their use in test kits and as vaccines 有权
来自博氏疏螺旋体的免疫活性蛋白，编码它们的核酸及其在测试试剂盒和疫苗中的应用

  • 专利标题： Immunologically active proteins from Borrelia burgdorferi, nucleic acids which encode them, and their use in test kits and as vaccines
  • 专利标题（中）： 来自博氏疏螺旋体的免疫活性蛋白，编码它们的核酸及其在测试试剂盒和疫苗中的应用
  • 申请号： US09242299
    申请日： 1999-02-12
  • 公开(公告)号： US06610301B1
    公开(公告)日： 2003-08-26
  • 发明人: Manfred Motz , Erwin Soutschek
  • 申请人： Manfred Motz , Erwin Soutschek
  • 优先权： DE19632862 19960814
  • 主分类号： A61K3902
  • IPC分类号： A61K3902
Immunologically active proteins from Borrelia burgdorferi, nucleic acids which encode them, and their use in test kits and as vaccines
摘要：
The present invention relates to immunologically active proteins from Borrelia burgdorferi which are present in a form which is free of other proteins derived from Borrelia burgdorferi and which exhibit the sequence of the protein 1829-22A, which has the amino acid sequence MKKFNLIIEALFAILLTACNFGLMEETKIALESSSKDVKNKILQIKKDAEDKGVNFAAFTSSETG SKVTNGGLALREAKIQAINEVEKFLKRIEEEALKLKEHGNSGQFLELFDLLLEVLESLEPIGIKG LKDFISEEAKCNPISTSERLIEVKVQIENKMEEVKRKQNLNKERKSNKGKKKK SEQ. ID NO.: 1 or a part sequence thereof having at least 10 consecutive amino acids, or exhibit the sequence of the protein 1829-22B, which has the amino acid sequence MIKYNKIILTLTLLASLLAACSLTGKARLESSVKDITNEIEKAIKEAEDAGVKTDAFTETQTGGK VAGPKIRAAKIRVADLTIKFLEATEEETITFKENGAGEDEFSGIYDLILNAAKAVEKIGMKDMTK TVEEAAKENPKTTANGIIEIVKVMKAKVENIKEKQTKNQK SEQ. ID NO.: 2 or a part sequence thereof having at least 10 consecutive amino acids.
摘要（中）：

本发明涉及由莱姆病螺旋体免疫活性的蛋白质，其存在于一种形式，其不含来自伯氏疏螺旋和其表现出的蛋白1829-22A，其具有氨基酸sequenceMKKFNLIIEALFAILLTACNFGLMEETKIALESSSKDVKNKILQIKKDAEDKGVNFAAFTSSETG SKVTNGGLALREAKIQAINEVEKFLKRIEEEALKLKEHGNSGQFLELFDLLLEVLESLEPIGIKG LKDFISEEAKCNPISTSERLIEVKVQIENKMEEVKRKQNLNKERKSNKGKKKK SEQ的序列衍生其它蛋白质。 或具有至少10个连续氨基酸的部分序列，或表现出具有氨基酸序列的蛋白质1829-22B的序列，其具有以下氨基酸序列：MIKYNKIILTLTLLASLLAACSLTGKARLESSVKDITNEIEKAIKEAEDAGVKTDAFTETQTGGK VAGPKIRAAKIRVADLTIKFLEATEEETITFKENGAGEDEFSGIYDLILNAAKAVEKIGMKDMTK TVEEAAKENPKTTANGIIEIVKVMKAKVENIKEKQTKNQK SEQ ID NO： ID号：2或其具有至少10个连续氨基酸的部分序列。

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