发明授权
- 专利标题： Heterocyclic sulfonamide inhibitors of beta amyloid production
- 专利标题（中）： β-淀粉样蛋白生成的杂环磺酰胺抑制剂
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申请号： US10014304申请日： 2001-12-11
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公开(公告)号： US06610734B2公开(公告)日： 2003-08-26
- 发明人: Anthony F. Kreft , Derek C. Cole , Kevin R. Woller , Joseph R. Stock , George Diamantidis , Dennis M. Kubrak , Kristina M. Kutterer , William J. Moore , David S. Casebier , Lynn Resnick
- 申请人： Anthony F. Kreft , Derek C. Cole , Kevin R. Woller , Joseph R. Stock , George Diamantidis , Dennis M. Kubrak , Kristina M. Kutterer , William J. Moore , David S. Casebier , Lynn Resnick
- 主分类号： A61K3138
- IPC分类号： A61K3138
摘要：
Compounds of Formula (I), wherein R1, R2, R3, R4, R5, R6, T, W, X, Y and Z are as defined herein are provided, together with pharmaceutically acceptable salt, hydrates and/or prodrugs thereof. Methods of using these compounds for inhibiting beta amyloid production and for treatment of Alzheimer's Disease and Down's syndrome are described.