发明授权
- 专利标题： Modulators of protein tyrosine phosphatases (PTPases)
- 专利标题（中）： 蛋白酪氨酸磷酸酶（PTPases）的调节剂
-
申请号： US09901367申请日： 2001-07-09
-
公开(公告)号： US06613903B2公开(公告)日： 2003-09-02
- 发明人: Henrik Sune Andersen , Thomas Kruse Hansen , Jesper Lau , Niels Peter Hundahl Moller , Ole Hvilsted Olsen , Frank Urban Axe , Farid Bakir , Yu Ge , Daniel Dale Holsworth , Luke Milburn Judge , Michael James Newman , Roy Teruyuki Uyeda , Barry Zvi Shapira
- 申请人： Henrik Sune Andersen , Thomas Kruse Hansen , Jesper Lau , Niels Peter Hundahl Moller , Ole Hvilsted Olsen , Frank Urban Axe , Farid Bakir , Yu Ge , Daniel Dale Holsworth , Luke Milburn Judge , Michael James Newman , Roy Teruyuki Uyeda , Barry Zvi Shapira
- 优先权： DK200001068 20000707
- 主分类号： C07D47102
- IPC分类号： C07D47102
摘要：
The present invention provides novel thienopyridines, novel compositions, methods of their use, and methods of their manufacture, where such compounds of Formula 1 are pharmacologically useful inhibitors of Protein Tyrosine Phosphatases (PTPase's) including PTP1B, T cell PTP, wherein X, R1, R2, R3, and R4 are defined more fully in the description. The compounds are useful in the treatment of type 1 diabetes, type 2 diabetes, impaired glucose tolerance, insulin resistance, obesity, and other diseases.
公开/授权文献
- US20020151561A1 Modulators of Protein Tyrosine Phosphatases (PTPases) 公开/授权日：2002-10-17
信息查询
