发明授权
- 专利标题： OB protein-polymer chimeras
- 专利标题（中）： OB蛋白聚合物嵌合体
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申请号： US08775066申请日： 1996-12-27
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公开(公告)号： US06620413B1公开(公告)日： 2003-09-16
- 发明人: Frederic DeSauvage , Nancy Levin , Richard Vandlen
- 申请人： Frederic DeSauvage , Nancy Levin , Richard Vandlen
- 主分类号： A61K39395
- IPC分类号： A61K39395
摘要：
The present invention concerns long-half derivative of the obesity protein OB. The invention specifically concerns OB protein-immunoglobulin chimeras and polyethylene glycol (PEG)-OB derivatives, which have extended half-life as compared to the corresponding native OB proteins. The invention further relates to methods for treating obesity by using the long half-life derivatives of OB.
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