发明授权
US06632946B2 Tetracyclic analogues of camptothecins, their preparation processes, their use as medicaments and the pharmaceutical compositions containing them
失效
喜树碱的四环类似物，其制备方法，它们作为药物的用途以及含有他们的药物组合物
- 专利标题： Tetracyclic analogues of camptothecins, their preparation processes, their use as medicaments and the pharmaceutical compositions containing them
- 专利标题（中）： 喜树碱的四环类似物，其制备方法，它们作为药物的用途以及含有他们的药物组合物
-
申请号： US09734167申请日： 2000-12-12
-
公开(公告)号： US06632946B2公开(公告)日： 2003-10-14
- 发明人: Dennis Bigg , Olivier Lavergne , Alain Rolland , Christophe Lanco , Gerard Ulibarri
- 申请人： Dennis Bigg , Olivier Lavergne , Alain Rolland , Christophe Lanco , Gerard Ulibarri
- 优先权： FR9716461 19971224
- 主分类号： C07D21378
- IPC分类号： C07D21378
摘要：
The invention relates to new tetracyclic analogues of camptothecin, their preparation processes, their use as medicaments and the pharmaceutical compositions containing them. Said analogues, which include in particular 3-hydroxy-3-(4-oxo-4,6-dihydroindolizino[1,2-b]quinoline-2-yl)pentanoic acid, have a powerful biological activity inhibiting topoisomerase I and/or topoisomerase II.
公开/授权文献
信息查询
