![3-[4-Substituted heterocyclyl)-pyrrol-2-ylmethylidene]-2- indolinone derivatives as kinase inhibitors](/docs/US/2003-11-04/US06642232B2/abs.jpg.600x600.jpg)
- 专利标题： 3-[4-Substituted heterocyclyl)-pyrrol-2-ylmethylidene]-2- indolinone derivatives as kinase inhibitors
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申请号： US10268082申请日： 2002-10-10
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公开(公告)号： US06642232B2公开(公告)日： 2003-11-04
- 发明人: Matthew Mattson , Tomas Vojkovsky , Congxin Liang , Peng Cho Tang , Huiping Guan
- 申请人： Matthew Mattson , Tomas Vojkovsky , Congxin Liang , Peng Cho Tang , Huiping Guan
- 主分类号： A61K315377
- IPC分类号： A61K315377
![3-[4-Substituted heterocyclyl)-pyrrol-2-ylmethylidene]-2- indolinone derivatives as kinase inhibitors](/abs-image/US/2003/11/04/US06642232B2/abs.jpg.150x150.jpg)
摘要：
The present invention relates to certain 3-[4-(substituted heterocyclyl)-pyrrol-2-ylmethylidene]-2-indolinone derivatives that inhibit kinases, in particular VEGFR and/or PDGFR kinases. Pharmaceutical compositions comprising these compounds, methods of treating diseases mediated by kinases utilizing pharmaceutical compositions comprising these compounds, and methods of preparing them are also disclosed.
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