发明授权
- 专利标题: Isoxazole compositions useful as inhibitors of ERK
- 专利标题(中): 用作ERK抑制剂的异恶唑组合物
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申请号: US10272622申请日: 2002-10-15
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公开(公告)号: US06649640B2公开(公告)日: 2003-11-18
- 发明人: Michael Hale , James Janetka , Francois Maltais , Jingrong Cao
- 申请人: Michael Hale , James Janetka , Francois Maltais , Jingrong Cao
- 主分类号: A61K31422
- IPC分类号: A61K31422
摘要:
Described herein are compounds that are useful as protein kinase inhibitors, especially inhibitors of ERK, having the formula: where A, B, R1, R2, T and Ht are described in the specification. The compounds are useful for treating diseases in mammals that are alleviated by a protein kinase inhibitor, particularly diseases such as cancer, inflammatory disorders, restenosis, and cardiovascular disease.
公开/授权文献
- US20030195241A1 Isoxazole compositions useful as inhibitors of ERK 公开/授权日:2003-10-16