Invention Grant
US06653478B2 Substituted benzimidazol-2-ones as vasopressin receptor antagonists and neuropeptide Y modulators
失效
取代的苯并咪唑-2-酮作为血管加压素受体拮抗剂和神经肽Y调节剂
- Patent Title: Substituted benzimidazol-2-ones as vasopressin receptor antagonists and neuropeptide Y modulators
- Patent Title (中): 取代的苯并咪唑-2-酮作为血管加压素受体拮抗剂和神经肽Y调节剂
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Application No.: US10047841Application Date: 2001-10-23
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Publication No.: US06653478B2Publication Date: 2003-11-25
- Inventor: Maud J. Urbanski , Joseph W. Gunnet, Jr. , Keith T. Demarest
- Applicant: Maud J. Urbanski , Joseph W. Gunnet, Jr. , Keith T. Demarest
- Main IPC: C07D40104
- IPC: C07D40104

Abstract:
The invention is directed to substituted benzimidazol-2-ones of Formula I, wherein A, X, Y, m, n, R1, R2, R3, R4, and R5 are as described in the specification, which are useful as vasopressin receptor antagonists or Neuropeptide Y Modulators for treating conditions such as aggression, obsessive-compulsive disorders, hypertension, dysmenorrhea, congestive heart failure/cardiac insufficiency, coronary vasospasm, cardiac ischemia, liver cirrhosis, renal vasospasm, renal failure, edema, ischemia, stroke, thrombosis, water retention, nephrotic syndrome, central nervous injuries, obesity, anorexia, hyperglycemia, diabetes, anxiety, depression, asthma, memory loss, sexual dysfunction, disorders of sleep and other circadian rhythms, and Cushing's disease.
Public/Granted literature
- US20030073842A1 Novel substituted benzimidazol-2-ones as vasopressin receptor antagonists and neuropeptide Y modulators Public/Granted day:2003-04-17
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