发明授权
- 专利标题： Fluorides of 4-substituted piperidine derivatives
- 专利标题（中）： 4-取代哌啶衍生物的氟化物
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申请号： US09914581申请日： 2001-08-30
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公开(公告)号： US06677330B1公开(公告)日： 2004-01-13
- 发明人: Yoichi Iimura , Takashi Kosasa , Yoshiharu Yamanishi , Hachiro Sugimoto , Yoshio Takeuchi , Tetsuo Shibata , Emiko Suzuki
- 申请人： Yoichi Iimura , Takashi Kosasa , Yoshiharu Yamanishi , Hachiro Sugimoto , Yoshio Takeuchi , Tetsuo Shibata , Emiko Suzuki
- 优先权： JP11-55755 19990303
- 主分类号： A61K3133
- IPC分类号： A61K3133
摘要：
The present invention provides a novel compound having an excellent acetylcholinesterase inhibitory effect. That is, it provides a 4-substituted piperidine compound fluoride represented by the following formula, a pharmaceutically acceptable salt thereof or hydrates thereof (provided that 1-benzyl-4-[(5,6-dimethoxy-2-fluoro-1-indanon)-2-yl]methylpiperidine, a pharmaceutically acceptable salt thereof and hydrates thereof are excluded). wherein R1 and R2 represent substituents.