发明授权
US06677373B2 Polymorphic B form of 3-(cyclopropylmethoxy)-4-[4-(methylsulfonyl)phenyl]-5,5-dimethyl-5H-furan-2-one
有权
3-(环丙基甲氧基)-4- [4-(甲基磺酰基)苯基] -5,5-二甲基-5H-呋喃-2-酮的多晶型B形式
- 专利标题: Polymorphic B form of 3-(cyclopropylmethoxy)-4-[4-(methylsulfonyl)phenyl]-5,5-dimethyl-5H-furan-2-one
- 专利标题(中): 3-(环丙基甲氧基)-4- [4-(甲基磺酰基)苯基] -5,5-二甲基-5H-呋喃-2-酮的多晶型B形式
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申请号: US10117854申请日: 2002-04-08
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公开(公告)号: US06677373B2公开(公告)日: 2004-01-13
- 发明人: Beatrice Calais , Evelyne Chassagneux , Jean-Michel Bonard
- 申请人: Beatrice Calais , Evelyne Chassagneux , Jean-Michel Bonard
- 优先权: EP99402482 19991008
- 主分类号: A61K3134
- IPC分类号: A61K3134
摘要:
This invention is related to a polymorphic B Form of 3-(cyclopropylmethoxy)-4-[4-(methylsulfonyl)phenyl]-5,5-dimethyl-5H-furan-2-one characterized by the following parameters: cristalline system Trigonal space group R-3 description hexagonal unit-cell dimensions a (Å) 18.183 b (Å) 18.183 c (Å) 26.950 &agr; (°) 90 &bgr; (°) 90 &ggr; (°) 120 unit-cell volume (Å3) 7716.5 number of molecules per unit-cell Z 18 Temperature of measurement (° K) 293 calculated specific gravity 1.303 weight absorption coefficient (cm−1) 2.11.
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