Polymorphic B form of 3-(cyclopropylmethoxy)-4-[4-(methylsulfonyl)phenyl]-5,5-dimethyl-5H-furan-2-one
    1.
    发明授权
    Polymorphic B form of 3-(cyclopropylmethoxy)-4-[4-(methylsulfonyl)phenyl]-5,5-dimethyl-5H-furan-2-one 有权
    3-(环丙基甲氧基)-4- [4-(甲基磺酰基)苯基] -5,5-二甲基-5H-呋喃-2-酮的多晶型B形式

    公开(公告)号:US06677373B2

    公开(公告)日:2004-01-13

    申请号:US10117854

    申请日:2002-04-08

    IPC分类号: A61K3134

    CPC分类号: C07D307/60

    摘要: This invention is related to a polymorphic B Form of 3-(cyclopropylmethoxy)-4-[4-(methylsulfonyl)phenyl]-5,5-dimethyl-5H-furan-2-one characterized by the following parameters: cristalline system Trigonal space group R-3 description hexagonal unit-cell dimensions a (Å) 18.183 b (Å) 18.183 c (Å) 26.950 &agr; (°) 90 &bgr; (°) 90 &ggr; (°) 120 unit-cell volume (Å3) 7716.5 number of molecules per unit-cell Z 18 Temperature of measurement (° K) 293 calculated specific gravity 1.303 weight absorption coefficient (cm−1) 2.11.

    摘要翻译: 本发明涉及3-(环丙基甲氧基)-4- [4-(甲基磺酰基)苯基] -5,5-二甲基-5H-呋喃-2-酮的多晶型B形式,其特征在于以下参数: