发明授权
US06680191B1 Isolated nucleic acid molecules coding for tumor rejection antigen precursors of members of the MAGE-C and MAGE-B FAMILIES and uses thereof
有权
编码MAGE-C和MAGE-B家族成员的肿瘤排斥抗原前体的分离的核酸分子及其用途
- 专利标题： Isolated nucleic acid molecules coding for tumor rejection antigen precursors of members of the MAGE-C and MAGE-B FAMILIES and uses thereof
- 专利标题（中）： 编码MAGE-C和MAGE-B家族成员的肿瘤排斥抗原前体的分离的核酸分子及其用途
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申请号： US09468433申请日： 1999-12-17
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公开(公告)号： US06680191B1公开(公告)日： 2004-01-20
- 发明人: Sophie Lucas , Thierry Boon-Falleur
- 申请人： Sophie Lucas , Thierry Boon-Falleur
- 主分类号： C12M120
- IPC分类号： C12M120
摘要：
The invention relates to isolated nucleic acid molecules which code for antigens expressed by tumor cells which maybe recognized by cytotoxic T cells, leading to lysis of the tumor cells which express it. This invention also relates to vectors which are designed to encode the antigen expressed by tumor cells and also to cells transfected by the nucleic acid molecules or vectors which comprise the nucleic acid molecules. Various therapeutic and diagnostic uses arising out of the properties of the nucleic acid molecules and the antigens for which these code are also part of this invention.
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