发明授权
- 专利标题: Aggrecanase molecules
- 专利标题(中): 聚集蛋白聚糖酶分子
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申请号: US09981953申请日: 2001-10-18
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公开(公告)号: US06689599B1公开(公告)日: 2004-02-10
- 发明人: Lisa A. Racie , Natalie C. Twine , Michael J. Agostino , Neil Wolfman , Elisabeth A. Morris
- 申请人: Lisa A. Racie , Natalie C. Twine , Michael J. Agostino , Neil Wolfman , Elisabeth A. Morris
- 主分类号: C12N964
- IPC分类号: C12N964
摘要:
Aggrecanase proteins and the nucleotides sequences encoding them as well as processes for producing them are disclosed. Methods for developing inhibitors of the aggrecanase enzymes and antibodies to the enzymes for treatment of conditions characterized by the degradation of aggrecan are also disclosed.
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