发明授权
- 专利标题： Antisense modulation of sphingosine-1-phosphate lyase expression
- 专利标题（中）： 鞘氨醇-1-磷酸裂合酶表达的反义调控
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申请号： US09967669申请日： 2001-09-28
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公开(公告)号： US06692960B2公开(公告)日： 2004-02-17
- 发明人: C. Frank Bennett , Susan M. Freier
- 申请人： C. Frank Bennett , Susan M. Freier
- 主分类号： C07H2104
- IPC分类号： C07H2104
摘要：
Antisense compounds, compositions and methods are provided for modulating the expression of sphingosine-1-phosphate lyase. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding sphingosine-1-phosphate lyase. Methods of using these compounds for modulation of sphingosine-1-phosphate lyase expression and for treatment of diseases associated with expression of sphingosine-1-phosphate lyase are provided.
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