A pneumatic tire production system comprises production lines each including a green tire building station for assembling unvulcanized members of pneumatic tires into green tires. The green tires are vulcanized at a vulcanizing station which includes at least one vulcanizing unit equipped with a plurality of vulcanizing molds. The number of the vulcanizing mold is determined so as to satisfy the vulcanizing capacity which is substantially equivalent to the number of green tires formed at the building station within a predetermined unit time. The system serves to minimize the intermediate stock amount of green tires due to minimized changeover between different types of tires to be alternately produced.