Invention Grant
US06703197B1 Human methionine synthase: cloning, and methods for evaluating risk of neural tube defects, cardiovascular disease, and cancer
失效
人甲硫氨酸合酶：克隆，评估神经管缺陷，心血管疾病和癌症风险的方法
- Patent Title: Human methionine synthase: cloning, and methods for evaluating risk of neural tube defects, cardiovascular disease, and cancer
- Patent Title (中): 人甲硫氨酸合酶：克隆，评估神经管缺陷，心血管疾病和癌症风险的方法
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Application No.: US08980326Application Date: 1997-11-26
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Publication No.: US06703197B1Publication Date: 2004-03-09
- Inventor: Roy A. Gravel , Rima Rozen , Daniel LeClerc , Philippe Goyette , Eric Campeau
- Applicant: Roy A. Gravel , Rima Rozen , Daniel LeClerc , Philippe Goyette , Eric Campeau
- Main IPC: C07H2102
- IPC: C07H2102
Abstract:
The invention features a method for detecting an increased likelihood of hyperhomocysteinemia and, in turn, an increased or decreased likelihood of neural tube defects or cardiovascular disease. The invention also features therapeutic methods for reducing the risk of neural tube defects, colon cancers and related cancers. Also provided are the sequences of the human methionine synthase gene and protein and compounds and kits for performing the methods of the invention.
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