发明授权
- 专利标题： Antisense inhibition of vascular endothelial growth factor receptor-1 expression
- 专利标题（中）： 反义抑制血管内皮生长因子受体-1表达
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申请号： US09953318申请日： 2001-09-13
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公开(公告)号： US06710174B2公开(公告)日： 2004-03-23
- 发明人: C. Frank Bennett , Andrew T. Watt
- 申请人： C. Frank Bennett , Andrew T. Watt
- 主分类号： C07H2104
- IPC分类号： C07H2104
摘要：
Antisense compounds, compositions and methods are provided for modulating the expression of vascular endothelial growth factor receptor-1. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding vascular endothelial growth factor receptor-1. Methods of using these compounds for modulation of vascular endothelial growth factor receptor-1 expression and for treatment of diseases associated with expression of vascular endothelial growth factor receptor-1 are provided.
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