A transparent, thin film gloved envelope is provided to be worn on the hand and arm of a person during manipulations and/or examination of hazardous or noxious articles or matter. While the article is held in the gloved hand the sleeve or skirt that was covering the arms can be reversed and rolled over to cover the article and thereafter sealed to form an enclosing envelope. An erectable support skeleton is provided to support the membranes forming an enclosure to allow manual examination of the article contained. The envelope may be of a substantial size, provided with two dependent gloves for two-handed manipulation and examination, and a filtered orifice is provided together with a culture bed inside the enclosure. The suspended enclosure is then useful as an inexpensive examination and culturing chamber.