A method for defining the operation of a plant for producing, conveying and packaging articles. The articles include rolls, such as rolls of paper material and the like. The plant includes the following operative sections: at least an apparatus for forming articles positioned upstream, at least a machine for packaging the articles in respective packs positioned downstream, and an apparatus for conveying the articles which is able to transfer the articles between the forming apparatus and the packaging apparatus. The method and the plant provide that, through a central control unit of the plant, starting from predefined setting data, operating parameters of the sections of the plant are determined.