An X-ray diagnosis apparatus includes an X-ray tube, an imaging system which detects X-rays emitted from the X-ray tube and transmitted through an object to be examined and generates X-ray image data, an arm which supports the X-ray tube and the imaging system, an arm support mechanism which rotatably and movably supports the arm, and a bed which holds the object between the X-ray tube and the imaging system. This X-ray diagnosis apparatus further includes a three-dimensional image generating unit which generates three-dimensional image data from volume data concerning the object, a display unit which displays the three-dimensional image data, an input device which designates an interest point on the displayed three-dimensional image data, and a controller which controls at least one of the arm support mechanism and the bed, such that the center of the X-ray image data generated by the imaging system is positioned on a portion of the object which substantially corresponds to the designated interest point.