发明授权
US06787660B1 Functional vitamin D derivatives and a method for determining 25-hydroxy-vitamin D and 1&agr;, dihydroxy-vitamin D
有权
功能性维生素D衍生物和一种测定25-羟基维生素D和1α二羟基维生素D的方法
- 专利标题： Functional vitamin D derivatives and a method for determining 25-hydroxy-vitamin D and 1&agr;, dihydroxy-vitamin D
- 专利标题（中）： 功能性维生素D衍生物和一种测定25-羟基维生素D和1α二羟基维生素D的方法
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申请号： US09720338申请日： 2001-02-20
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公开(公告)号： US06787660B1公开(公告)日： 2004-09-07
- 发明人: Franz Paul Armbruster , Wolfgang Voelter , Jens Tampe , Christian Birkmayer
- 申请人： Franz Paul Armbruster , Wolfgang Voelter , Jens Tampe , Christian Birkmayer
- 优先权： DE19828379 19980625; DE19840435 19980904
- 主分类号： C07J40100
- IPC分类号： C07J40100
摘要：
Vitamin D compounds of formula (I) with a label attached to a spacer group in the 3 position are disclosed. In the above formula (I), X is an optionally substituted hydrocarbon group with a length of 0.8-4.2 nm, optionally containing the heteroatoms S, O, N or P; Y is H or OH; A is a label capable of binding with high affinity to a protein; R is an optionally substituted hydrocarbon side chain of a D vitamin or a D vitamin metabolite. Also disclosed is the preparation of formula (I).
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