发明授权
- 专利标题: Certain 1,3-disubstituted isoquinoline derivatives
- 专利标题(中): 某些1,3-二取代异喹啉衍生物
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申请号: US09852850申请日: 2001-05-11
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公开(公告)号: US06790844B2公开(公告)日: 2004-09-14
- 发明人: Kohshi Ueno , Atsushi Sasaki , Koki Kawano , Tadashi Okabe , Noritaka Kitazawa , Keiko Takahashi , Noboru Yamamoto , Yuichi Suzuki , Manabu Matsunaga , Atsuhiko Kubota
- 申请人: Kohshi Ueno , Atsushi Sasaki , Koki Kawano , Tadashi Okabe , Noritaka Kitazawa , Keiko Takahashi , Noboru Yamamoto , Yuichi Suzuki , Manabu Matsunaga , Atsuhiko Kubota
- 优先权: JP9-284290 19971002
- 主分类号: A61K3133
- IPC分类号: A61K3133
摘要:
Condensed pyridine compounds represented by formula (I): wherein: R1 and R3 are, independently, hydrogen, halogen, lower alkyl, or lower alkoxy; R2 represents an amino substituent; ring A is a benzene ring, pyridine ring, thiophene ring, or furan ring; and B represents a substituent containing a ring structure. Also, pharmaceutically acceptable salt and hydrates thereof. These compounds are clinically useful medicaments having; serotonin antagonism, and in particular, for treating, ameliorating, or preventing spastic paralysis. They are also useful as central muscle relaxants for ameliorating myotonia.
公开/授权文献
- US20020013460A1 Condensed pyridine compound 公开/授权日:2002-01-31
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