发明授权
- 专利标题: In vivo stimulation of angiogenic activity
- 专利标题(中): 体内刺激血管生成活性
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申请号: US09985159申请日: 2001-11-01
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公开(公告)号: US06793918B2公开(公告)日: 2004-09-21
- 发明人: Berndt Enholm , Didier Branellec , Seppo Ylae-Herttuala , Ralf Pettersson , Erika Bergsten , Ulf Eriksson , Kari Alitalo , Aude Le Roux
- 申请人: Berndt Enholm , Didier Branellec , Seppo Ylae-Herttuala , Ralf Pettersson , Erika Bergsten , Ulf Eriksson , Kari Alitalo , Aude Le Roux
- 主分类号: A61K4800
- IPC分类号: A61K4800
摘要:
Angiogenesis is stimulated by introducing two replication-deficient adenovirus vectors to the endothelial cells or proximate to the endothelial cells of an organism. The first vector encodes VEGF-B167 or a fragment or conservative substitution thereof, the second vector encodes VEGF-A or VEGF-C, or fragments or conservative substitutions thereof.
公开/授权文献
- US20030165464A1 In vivo stimulation of angiogenic activity 公开/授权日:2003-09-04
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