发明授权
US06811975B2 Phosphorothioate oligonucleotides having modified internucleoside linkages 失效
具有修饰的核苷间键的硫代磷酸酯寡核苷酸

  • 专利标题: Phosphorothioate oligonucleotides having modified internucleoside linkages
  • 专利标题(中): 具有修饰的核苷间键的硫代磷酸酯寡核苷酸
  • 申请号: US09805630
    申请日: 2001-03-14
  • 公开(公告)号: US06811975B2
    公开(公告)日: 2004-11-02
  • 发明人: Phillip Dan CookMuthiah Manoharan
  • 申请人: Phillip Dan CookMuthiah Manoharan
  • 主分类号: C12Q168
  • IPC分类号: C12Q168
Phosphorothioate oligonucleotides having modified internucleoside linkages
摘要:
Novel compounds that mimic and/or modulate the activity of wild-type nucleic acids. In general, the compounds are phosphorothioate oligonucleotides wherein the 5′-terminal internucleoside linkage or the 5′- and 3′-terminal linkages are modified.
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