发明授权
US06811975B2 Phosphorothioate oligonucleotides having modified internucleoside linkages
失效
具有修饰的核苷间键的硫代磷酸酯寡核苷酸
- 专利标题: Phosphorothioate oligonucleotides having modified internucleoside linkages
- 专利标题(中): 具有修饰的核苷间键的硫代磷酸酯寡核苷酸
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申请号: US09805630申请日: 2001-03-14
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公开(公告)号: US06811975B2公开(公告)日: 2004-11-02
- 发明人: Phillip Dan Cook , Muthiah Manoharan
- 申请人: Phillip Dan Cook , Muthiah Manoharan
- 主分类号: C12Q168
- IPC分类号: C12Q168
摘要:
Novel compounds that mimic and/or modulate the activity of wild-type nucleic acids. In general, the compounds are phosphorothioate oligonucleotides wherein the 5′-terminal internucleoside linkage or the 5′- and 3′-terminal linkages are modified.
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