发明授权
- 专利标题: Preparation of a recombinant protein in a prokaryotic host cell
- 专利标题(中): 在原核宿主细胞中制备重组蛋白
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申请号: US09916229申请日: 2001-07-27
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公开(公告)号: US06821755B2公开(公告)日: 2004-11-23
- 发明人: Rolf-Günther Werner , Klaus Bergemann , Friedrich Götz , Andreas Peschel
- 申请人: Rolf-Günther Werner , Klaus Bergemann , Friedrich Götz , Andreas Peschel
- 优先权: DE10037111 20000727
- 主分类号: C12P2102
- IPC分类号: C12P2102
摘要:
The invention relates to advantageous processes for preparing heterologous proteins in prokaryotic host cells by improved codon use and/or expression of tRNAs which code for codons occurring rarely in said host cell.
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