Invention Grant
- Patent Title: Fenofibrate-cyclodextrin inclusion complexes and their pharmaceutical composition
- Patent Title (中): 非诺贝特 - 环糊精包合物及其药物组成
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Application No.: US10338562Application Date: 2003-01-07
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Publication No.: US06828334B2Publication Date: 2004-12-07
- Inventor: Suresh Kumar Gidwani , Purushottam Sharshikant Singnurkar
- Applicant: Suresh Kumar Gidwani , Purushottam Sharshikant Singnurkar
- Main IPC: A61K900
- IPC: A61K900

Abstract:
The present invention relates to pharmaceutical compositions containing fenofibrate in the form of an inclusion complex with cyclodextrin, having high dissolution profile and in vivo enhanced bioavailability as compared with plain micronized fenofibrate compositions. An inclusion complex has a molar ratio of fenofibrate (preferably in micronized form) to cyclodextrin of from about 1:0.5 to about 1:4, preferably from about 1:1 to about 1:2. The immediate release fenofibrate composition is preferably in the form of a tablet or in the form of granules inside a capsule.
Public/Granted literature
- US20030220293A1 Fenofibrate-cyclodextrin inclusion complexes and their pharmaceutical composition Public/Granted day:2003-11-27
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