发明授权
US06852861B2 Preparation of 1H-imidazo [4,5-C] quinolin-4-amines via 1H-imidazo [4,5-C] quinolin-4-phthalimide intermediates
失效
通过1H-咪唑并[4,5-C]喹啉-4-邻苯二甲酰亚胺中间体制备1H-咪唑并[4,5-C]喹啉-4-胺
- 专利标题: Preparation of 1H-imidazo [4,5-C] quinolin-4-amines via 1H-imidazo [4,5-C] quinolin-4-phthalimide intermediates
- 专利标题(中): 通过1H-咪唑并[4,5-C]喹啉-4-邻苯二甲酰亚胺中间体制备1H-咪唑并[4,5-C]喹啉-4-胺
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申请号: US10626036申请日: 2003-07-23
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公开(公告)号: US06852861B2公开(公告)日: 2005-02-08
- 发明人: Valeriano Merli , Silvia Mantovani , Stefano Bianchi
- 申请人: Valeriano Merli , Silvia Mantovani , Stefano Bianchi
- 申请人地址: HU Debrecen
- 专利权人: Biogal Gyogyszergyar Rt.
- 当前专利权人: Biogal Gyogyszergyar Rt.
- 当前专利权人地址: HU Debrecen
- 代理机构: Kenyon & Kenyon
- 主分类号: A61K31/47
- IPC分类号: A61K31/47 ; A61P31/12 ; C07D471/04 ; C07D515/12
摘要:
The invention provides 1H-imidazo(4,5-C)quinolin-4-phthalimide intermediates useful in the synthesis of 1H-imidazo(4,5-C)quinoline-4-amines, particularly Imiquimod. The invention further provides a method for making the intermediates and a method for making 1H-imidazo(4,5-C)quinoline-4-amines via the intermediates.
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