发明授权
- 专利标题： Substituted biaryl amides as C5a receptor modulators
- 专利标题（中）： 取代的联芳酰胺作为C5a受体调节剂
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申请号： US10401270申请日： 2003-03-27
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公开(公告)号： US06858637B2公开(公告)日： 2005-02-22
- 发明人: Yang Gao , Alan J. Hutchison , Wallace C. Pringle , Andrew Thurkauf , Taeyoung Yoon , He Zhao
- 申请人： Yang Gao , Alan J. Hutchison , Wallace C. Pringle , Andrew Thurkauf , Taeyoung Yoon , He Zhao
- 申请人地址： US CT Branford
- 专利权人： Neurogen Corporation
- 当前专利权人： Neurogen Corporation
- 当前专利权人地址： US CT Branford
- 代理商 Ann T. Kadlecek; Seth Fidel
- 主分类号： A61K31/165
- IPC分类号： A61K31/165 ; A61K31/341 ; A61K31/355 ; A61K31/40 ; A61K31/401 ; A61K31/4025 ; A61K31/4164 ; A61K31/4178 ; C07D207/32 ; C07D233/56 ; C07D307/40
摘要：
Substituted biaryl amides of Formula I are provided. Such compounds are ligands that may be used to modulate C5a receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological C5a receptor activation in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for using them to treat such disorders are provided, as are methods for using such ligands for receptor localization studies.
公开/授权文献
- US20040048913A1 Substituted biaryl amides as C5a receptor modulators 公开/授权日：2004-03-11
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