- 专利标题: Immunization of dairy cattle with GapC protein against Streptococcus infection
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申请号: US09878781申请日: 2001-06-11
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公开(公告)号: US06866855B2公开(公告)日: 2005-03-15
- 发明人: Alexandra J. Bolton , Jose Perez-Casal , Michael Fontaine , Andrew A. Potter
- 申请人: Alexandra J. Bolton , Jose Perez-Casal , Michael Fontaine , Andrew A. Potter
- 申请人地址: CA
- 专利权人: University of Saskatchewan
- 当前专利权人: University of Saskatchewan
- 当前专利权人地址: CA
- 代理机构: Robins & Pasternak LLP
- 主分类号: A61K39/00
- IPC分类号: A61K39/00 ; C07K14/315 ; C12N1/21 ; A61K39/09 ; A61K38/00 ; A61K39/38 ; C07K1/00 ; A61K30/02
摘要:
The GapC plasmin binding protein genes of Streptococcus dysgalactiae (S. dysgalactiae), Streptococcus agalactiae (S. agalactiae), Streptococcus uberis (S. uberis), Streptococcus parauberis (S. parauberis), and Streptococcus iniae (S. iniae) are described, as well as the recombinant production of the GapC proteins therefrom. Also described is the use of the GapC proteins from those species in vaccine compositions to prevent or treat bacterial infections in general, and mastitis in particular.
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