Invention Grant
US06875758B2 Method of treating hyperlipidemic and hyperglycemic conditions in mammals using pregnadienols and pregnadienones
有权
使用孕二烯醇和孕代孕酮治疗哺乳动物高脂血症和高血糖病症的方法
- Patent Title: Method of treating hyperlipidemic and hyperglycemic conditions in mammals using pregnadienols and pregnadienones
- Patent Title (中): 使用孕二烯醇和孕代孕酮治疗哺乳动物高脂血症和高血糖病症的方法
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Application No.: US10385936Application Date: 2003-03-14
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Publication No.: US06875758B2Publication Date: 2005-04-05
- Inventor: Ram Pratap , Ram Chandra Gupta , Ramesh Chander , Ashok Kumar Khanna , Arvind Kumar Srivastava , Deepak Raina , Satyavan Singh , Savita Srivastava , Anil Kumar Rastogi , Omkar Prasad Asthana , Swarn Nityanand , Nitya Anand , Ashim Ghatak , Narinder Kumar Kapoor , Sukh Dev
- Applicant: Ram Pratap , Ram Chandra Gupta , Ramesh Chander , Ashok Kumar Khanna , Arvind Kumar Srivastava , Deepak Raina , Satyavan Singh , Savita Srivastava , Anil Kumar Rastogi , Omkar Prasad Asthana , Swarn Nityanand , Nitya Anand , Ashim Ghatak , Narinder Kumar Kapoor , Sukh Dev
- Applicant Address: IN New Delhi
- Assignee: Council of Scientific & Industrial Research
- Current Assignee: Council of Scientific & Industrial Research
- Current Assignee Address: IN New Delhi
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner, L.L.P.
- Priority: IN67DEL/99 19990112
- Main IPC: C07J13/00
- IPC: C07J13/00 ; A61K31/56 ; A61K31/59

Abstract:
The invention provides a method of using pregnadienones and pregnadienols represented by the structural formula (I) as shown herein below Wherein X═OH or O or combination thereof and positioning of olefinic bonds are at 4(5); 5(6); 16(17); 17(20) or various combinations and said compounds containing at least one olefinic bond in or on their D-ring for the treatment of hyperlipidemic and hyperglycemic conditions in mammals, said method comprising administering an effective amount of the said compounds to the recipient mammals.
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