发明授权
- 专利标题： Formation of polyampholytes in the presence of a polyion
- 专利标题（中）： 在聚阴离子存在下形成聚阴离子
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申请号： US10095752申请日： 2002-03-11
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公开(公告)号： US06881576B2公开(公告)日： 2005-04-19
- 发明人: Jon A. Wolff , James E. Hagstrom , Vladimir G. Budker , Vladimir S. Trubetskoy
- 申请人： Jon A. Wolff , James E. Hagstrom , Vladimir G. Budker , Vladimir S. Trubetskoy
- 申请人地址： US WI Madison
- 专利权人： Mirus Bio Corporation
- 当前专利权人： Mirus Bio Corporation
- 当前专利权人地址： US WI Madison
- 代理商 Mark K. Johnson
- 主分类号： A61K47/48
- IPC分类号： A61K47/48 ; C12N15/88 ; C12N15/64
摘要：
A polyampholyte is utilized in a condensed polynucleotide complex for purposes of nucleic acid delivery to a cell. The complex can be formed with an appropriate amount of positive and/or negative charge such that the resulting complex can be delivered to the extravascular space and may be further delivered to a cell.
公开/授权文献
- US20020160515A1 Formation of polyampholytes in the presence of a polyion 公开/授权日：2002-10-31