发明授权
- 专利标题： Nucleic acid constructs
- 专利标题（中）： 核酸构建体
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申请号： US09434830申请日： 1999-11-05
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公开(公告)号： US06881723B1公开(公告)日： 2005-04-19
- 发明人: Deborah L. Fuller , James T. Fuller
- 申请人： Deborah L. Fuller , James T. Fuller
- 申请人地址： US WI Madison
- 专利权人： Powderject Vaccines, Inc.
- 当前专利权人： Powderject Vaccines, Inc.
- 当前专利权人地址： US WI Madison
- 代理机构： Foley & Lardner, LLP
- 主分类号： A61K39/385
- IPC分类号： A61K39/385 ; A61K48/00 ; C07H21/04 ; C12N15/74
摘要：
Recombinant nucleic acid molecules are described. The molecules have a first sequence encoding a Hepatitis B virus core antigen and a second sequence encoding at least one T cell epitope inserted within the first sequence. Vectors and compositions containing these molecules are also described. Methods of eliciting an immune response using these molecules are also described.