发明授权
- 专利标题： Kinesin inhibitors
-
申请号： US09791339申请日： 2001-02-23
-
公开(公告)号： US06890933B1公开(公告)日： 2005-05-10
- 发明人: Yan Feng , Tarun M. Kapoor , Thomas Mayer , Zoltan Maliga , Timothy J. Mitchison , Justin Yarrow
- 申请人： Yan Feng , Tarun M. Kapoor , Thomas Mayer , Zoltan Maliga , Timothy J. Mitchison , Justin Yarrow
- 申请人地址： US MA Cambridge
- 专利权人： President and Fellows of Harvard College
- 当前专利权人： President and Fellows of Harvard College
- 当前专利权人地址： US MA Cambridge
- 代理机构： Choate, Hall & Stewart
- 代理商 Brenda Herschbach Jarrell; Nadege M. Lagneau
- 主分类号： C07D471/14
- IPC分类号： C07D471/14 ; A61K31/437 ; C02D471/04
摘要：
The present invention provides for compounds, compositions, methods and systems for inhibiting cell growth. More specifically, the present invention provides for methods, compounds and compositions which are capable of inhibiting mitosis in metabolically active cells. Compounds, compositions and methods of the present invention inhibit the activity of a protein involved in the assembly and maintenance of the mitotic spindle. One class of proteins which acts on the mitotic spindle is the family of mitotic kinesins, a subset of the kinesin superfamily.
信息查询
