发明授权
- 专利标题: Fluorescent probe for the quantitation of zinc
- 专利标题(中): 用于定量锌的荧光探针
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申请号: US10203658申请日: 2001-02-28
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公开(公告)号: US06903226B2公开(公告)日: 2005-06-07
- 发明人: Tetsuo Nagano , Kazuya Kikuchi , Tomoya Hirano
- 申请人: Tetsuo Nagano , Kazuya Kikuchi , Tomoya Hirano
- 申请人地址: JP Tokyo JP Tokyo
- 专利权人: Daiichi Pure Chemicals Co., Ltd.,Tetsuo Nagano
- 当前专利权人: Daiichi Pure Chemicals Co., Ltd.,Tetsuo Nagano
- 当前专利权人地址: JP Tokyo JP Tokyo
- 代理机构: Greenblum & Bernstein, P.L.C.
- 优先权: JP2000-050869 20000228
- 国际申请: PCT/JP01/01503 WO 20010228
- 国际公布: WO01/62755 WO 20010830
- 主分类号: C07D311/82
- IPC分类号: C07D311/82 ; C07D493/10 ; C09B11/24 ; C09B11/28 ; C07D311/78
摘要:
A compound represented by general formula (IA) or a salt thereof useful as a fluorescent probe for zinc: wherein R1 and R2 represent a hydrogen atom or a group represented by formula (A), wherein X1, X2, X3, and X4 represent a hydrogen atom, an alkyl group, a 2-pyridylmethyl group, or a protective group for an amino group, and m and n represent 0 or 1 provided that R1 and R2 do not simultaneously represent hydrogen atoms; R3 and R4 represent a hydrogen atom or a halogen atom; and R5 and R6 represent a hydrogen atom, an alkylcarbonyl group, or an alkylcarbonyloxymethyl group, and R7 represents a hydrogen atom or an alkyl group.
公开/授权文献
- US20030162298A1 Flourescent probe for the quantitation of zinc 公开/授权日:2003-08-28
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