发明授权
US06911200B2 Methods of treating neoplasia with combination of target-cell specific adenovirus, chemotherapy and radiation
失效
用靶细胞特异性腺病毒，化学疗法和放射线联合治疗瘤形成的方法
- 专利标题： Methods of treating neoplasia with combination of target-cell specific adenovirus, chemotherapy and radiation
- 专利标题（中）： 用靶细胞特异性腺病毒，化学疗法和放射线联合治疗瘤形成的方法
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申请号： US09814357申请日： 2001-03-21
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公开(公告)号： US06911200B2公开(公告)日： 2005-06-28
- 发明人: De-Chao Yu , Yu Chen , Daniel R. Henderson
- 申请人： De-Chao Yu , Yu Chen , Daniel R. Henderson
- 申请人地址： US CA Foster City
- 专利权人： Cell Genesys, Inc.
- 当前专利权人： Cell Genesys, Inc.
- 当前专利权人地址： US CA Foster City
- 代理机构： DLA Piper Rudnick Gray Cary US LLP
- 代理商 Steven B. Kelber
- 主分类号： A61K31/7048
- IPC分类号： A61K31/7048 ; A61K38/21 ; A61K38/22 ; A61K48/00 ; C12N15/861 ; A01N63/00
摘要：
The invention provides methods of treating neoplasia using combinations of target cell-specific replication competent adenoviral vectors and chemotherapy, radiation therapy or combinations thereof. The adenoviral vectors are target cell-specific for the particular type of neoplasia for which treatment is necessary and the combination with the chemotherapy and/or radiation leads to synergistic treatment over existing adenoviral therapy or traditional chemotherapy and radiation therapy.