发明授权
US06919349B2 Spiro compounds and adhesion molecule inhibitors containing the same as the active ingredient
失效
含有与活性成分相同的螺环化合物和粘附分子抑制剂
- 专利标题： Spiro compounds and adhesion molecule inhibitors containing the same as the active ingredient
- 专利标题（中）： 含有与活性成分相同的螺环化合物和粘附分子抑制剂
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申请号： US10381367申请日： 2001-09-25
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公开(公告)号： US06919349B2公开(公告)日： 2005-07-19
- 发明人: Toshiya Takahashi , Takeshi Ishigaki , Miyuki Funahashi , Koji Taniguchi , Masayuki Kaneko , Mie Kainoh , Hiroyuki Meguro
- 申请人： Toshiya Takahashi , Takeshi Ishigaki , Miyuki Funahashi , Koji Taniguchi , Masayuki Kaneko , Mie Kainoh , Hiroyuki Meguro
- 申请人地址： JP Tokyo
- 专利权人： Toray Industries, Inc.
- 当前专利权人： Toray Industries, Inc.
- 当前专利权人地址： JP Tokyo
- 代理机构： Birch, Stewart, Kolasch & Birch, LLP
- 优先权： JP2000-289658 20000925
- 国际申请： PCT/JP01/08290 WO 20010925
- 国际公布： WO02/24697 WO 20020328
- 主分类号： A61P1/04
- IPC分类号： A61P1/04 ; A61P1/16 ; A61P11/06 ; A61P13/12 ; A61P17/00 ; A61P19/02 ; A61P27/14 ; A61P27/16 ; A61P29/00 ; A61P37/06 ; A61P37/08 ; A61P43/00 ; C07D471/10 ; A61K31/438
摘要：
Disclosed are novel spiro derivatives and their medical uses, especially as adhesion molecule inhibitors useful for therapies of inflammatory diseases. The spiro derivative according to the present invention has the chemical structure, for example, represented by the following Formula (31):
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