发明授权
- 专利标题: Inhibitors of β-lactamase
- 专利标题(中): β-内酰胺酶抑制剂
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申请号: US10411484申请日: 2003-04-08
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公开(公告)号: US06921756B2公开(公告)日: 2005-07-26
- 发明人: Jeffrey M. Besterman , Jubrail Rahil , Arkadii Vaisburg
- 申请人: Jeffrey M. Besterman , Jubrail Rahil , Arkadii Vaisburg
- 申请人地址: CA Quebec
- 专利权人: MethylGene, Inc.
- 当前专利权人: MethylGene, Inc.
- 当前专利权人地址: CA Quebec
- 代理机构: McDonnell Boehnen Hulbert & Berghoff LLP
- 主分类号: C07F9/24
- IPC分类号: C07F9/24 ; C07F9/38 ; C07F9/40 ; C07F9/42 ; C07F9/44 ; C07F9/572 ; C07F9/58 ; C07F9/60 ; C07F9/6506 ; C07F9/6524 ; C07F9/653 ; C07F9/6539 ; C07F9/6541 ; C07F9/655 ; C07F9/6553 ; C07F9/6558 ; A61K31/662 ; A61K31/66 ; A61P31/04
摘要:
The invention relates to bacterial antibiotic resistance and, in particular, to compositions and methods for overcoming bacterial antibiotic resistance. The invention provides novel β-lactamase inhibitors, which are structurally unrelated to the natural product and semi-synthetic β-lactamase inhibitors presently available, and which do not require a β-lactam pharmacophore. The invention also provides pharmaceutical compositions and methods for inhibiting bacterial growth.
公开/授权文献
- US20040082546A1 Novel Inhibitors of beta-lactamase 公开/授权日:2004-04-29